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pentobarbital will decrease the extent or influence of dutasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.pentobarbital decreases amounts of elvitegravir/cobicistat/emtricitabine/tenofovir DF by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Might cause loss of virologic r